张秀莉课题组 | 3D Bioprinting

Extrusion-based bioprinter

We developed an extrusion-based bioprinter in lab featuring temperature-controllable nozzle and substrate. The bioprinter is commercially available.

Extrusion-based bioprinter

We developed an extrusion-based bioprinter in lab featuring temperature-controllable nozzle and substrate. The bioprinter is commercially available.

Bioink

We invented a strategy to develop “ideal organ-specific bioink” based on decellularized matrix and corresponding additives, and developed ideal liver-printing bioink, kidney-printing bioink, tumor-printing bioink, etc. These bioinks are commercially available.

We printed an artificial blood vessel with gelatin and sodium alginate by controlling their polymerization. The thickness of the wall and the diameter of the lumen can be readily controlled. The inner wall of the artificial blood vessel can be seeded with HUVEC uniformly. The more is coming.

3D-bioprinted blood vessel

3D-printed liver lobule

We printed artificial liver lobule, inserted it into a microfluidic chip, and used this hybrid device to test the drug candidates. The more is coming.

3D-printed liver lobule

We printedan artificial breast tumor with lab-made bio-ink and used it to study the SAR of 13 ﬂavone-7-phosphoramidate Derivatives. More is coming.

3D-bioprinted breast tumor

We printedan artificial breast tumor with lab-made bio-ink and used it to study the SAR of 13 ﬂavone-7-phosphoramidate Derivatives. More is coming.

3D-bioprinted breast tumor